| 摘要 |
A method for the treatment of erectile dysfunction comprises instilling intra meatally an aqueous solution containing prostaglandin-containing liposomes, a lysing agent for lysing the liposomes, and a papaverine solution. A pharmaceutical composition for treating erectile dysfunction comprises a three-component system. The first component comprises a predetermined amount of prostaglandin-containing liposomes, preferably lyopholized. The second component comprises a predetermined volume of an aqueous solution containing a lysing agent, preferably PEG(9) octylphenyl ether, for lysing the liposomes. The third component comprises a papaverine solution. Dissolution of the prostaglandin-containing liposomes and addition of the papaverine solution to the mixture yields a liquid composition suitable for application to the penis, preferably intra meatally, to effect erection.
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