| 发明名称 |
Morpholine and thiomorpholine tachykinin receptor antagonists |
| 摘要 |
Substituted heterocycles of the general structural formula: <CHEM> are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia. |
| 申请公布号 |
EP0577394(B1) |
申请公布日期 |
1999.11.10 |
| 申请号 |
EP19930305086 |
申请日期 |
1993.06.29 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DORN, CONRAD P.;HALE, JEFFREY J.;MACCOSS, MALCOLM;MILLS, SANDER G.;LADDUWAHETTY, TAMARA;SHAH, SHRENIK K. |
| 分类号 |
A61K31/535;A61K31/5355;A61K31/5375;A61K31/54;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P25/04;A61P25/06;A61P29/00;C01B15/013;C07D;C07D265/30;C07D265/32;C07D279/12;C07D413/04;C07D413/06;C07D413/14;C07D417/04 |
主分类号 |
A61K31/535 |
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