Ionophoretic device for transdermal administration of medicaments, and disposable assembly forming part of such device

摘要

PCT No. PCT/FR95/01509 Sec. 371 Date May 12, 1997 Sec. 102(e) Date May 12, 1997 PCT Filed Nov. 16, 1995 PCT Pub. No. WO96/14896 PCT Pub. Date May 23, 1996The device comprises a reservoir (3) containing an active principle in ionized form, first (1) and second (2) electrodes in contact with a face of the reservoir (3) and the skin (6) of the patient, respectively, the other face of the reservoir being applied to the skin (6) of the patient and means (5) for circulating selectively an electric current between said electrodes in order to help the passage of a flow of active principle under the patient's skin. The device further comprises a) a control grid (11) arranged on the face of the reservoir (3) which is intended to be applied to the skin (6) of the patient and b) control means (10), (9), (13) for cutting off the assistance current during a predetermined period of time and to circulate a reverse current between the grid (11) and the first electrode (1) which is intended to cancel substantially the passive flow of ions of the active principle which would otherwise pass under the patient's skin.