发明名称 |
PTP 1D: a novel protein tyrosine phosphatase |
摘要 |
A novel protein tyrosine phosphatase is the protein designated PTP 1D. The PTP 1D protein may be produced by recombinant means, for example using a nucleic acid construct encoding the protein as provided herein. Also disclosed is an antibody specific for an epitope of PTP 1D, protein. Methods for identifying compounds which bind to a PTP 1D protein and inhibit or stimulate its enzymatic activity, pharmaceutical compositions comprising PTP 1D, and methods for treating a disease associated with PTP 1D protein using such compositions, are provided.
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申请公布号 |
US5981251(A) |
申请公布日期 |
1999.11.09 |
申请号 |
US19950448250 |
申请日期 |
1995.05.23 |
申请人 |
MAX PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
ULLRICH, AXEL;VOGEL, WOLFGANG |
分类号 |
C12N15/09;A61K38/00;A61K38/45;A61P43/00;C07H21/04;C07K14/47;C07K14/705;C07K16/40;C12N9/16;C12N15/55;C12P21/08;C12Q1/34;C12Q1/68;G01N33/573;(IPC1-7):C07K14/435 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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