NOVEL METHODS FOR THE PRODUCTION OF GELATIN AND FULL-LENGTH TRIPLE HELICAL COLLAGEN RECOMBINANT CELLS
摘要
Methods are disclosed for simplified recombinant production of fibrillar collagens. DNAs encoding fibrillar collagen monomers lacking the N propeptide, the C propeptide, or both propeptides are introduced into recombinant host cells and expressed. Trimeric collagen is recovered from the recombinant host cells.
申请公布号
CA2269148(A1)
申请公布日期
1999.11.08
申请号
CA19992269148
申请日期
1999.04.23
申请人
GENOTYPES, INC.;COHESION TECHNOLOGIES, INC.
发明人
OLSEN, DAVID R.;CHISHOLM, GEORGE E., IV;HITZEMAN, RONALD A.;MCMULLIN, HUGH;CHANG, ROBERT