发明名称 |
ASSAY FOR METHYLATION IN THE GST-PI GENE |
摘要 |
A diagnostic or prognostic assay is disclosed for a disease or condition characterised by abnormal methylation of cytosine at a site or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g. prostate cancer and liver cancer). The assay comprises: (i) isolating DNA from said subject, and (ii) determining (e.g. by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences.
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申请公布号 |
CA2326494(A1) |
申请公布日期 |
1999.11.04 |
申请号 |
CA19992326494 |
申请日期 |
1999.04.23 |
申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION |
发明人 |
MOLLOY, PETER LAURENCE;MILLAR, DOUGLAS S.;CLARK, SUSAN JOY |
分类号 |
C12N15/09;C12N9/10;C12N15/54;C12Q1/48;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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