发明名称 |
SOLID SUPPORTED SYNTHESIS OF SULFONATED 2-OXOPIPERAZINES |
摘要 |
<p>The subject invention involves processes for making 2-oxopiperazine and homologous compounds using a solid support resin by (a) removing the protecting group from a N-protected amino acid ester of the resin (if present), (b) reacting the resulting unprotected resin ester with a sulfonyl chloride, (c) reacting the resulting intermediate with a N-protected amino alcohol, (d) removing the N-protecting group from the N from the amino alcohol, and (e) cleaving/cyclizing the product from the resin.</p> |
申请公布号 |
WO9955684(A1) |
申请公布日期 |
1999.11.04 |
申请号 |
WO1999US09091 |
申请日期 |
1999.04.27 |
申请人 |
THE PROCTER & GAMBLE COMPANY;GOLEBIOWSKI, ADAM;KLOPFENSTEIN, SEAN, REES |
发明人 |
GOLEBIOWSKI, ADAM;KLOPFENSTEIN, SEAN, REES |
分类号 |
C07D241/08;C07D243/08;C07D487/04;(IPC1-7):C07D241/08 |
主分类号 |
C07D241/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|