MEMBRANE-PERMEANT PHOSPHOINOSITIDES

摘要

Membrane-permeant phosphoinositides, including phosphatidylinositol phosphat e esters, are described. A membrane-permeant phosphoinositide includes groups that neutralize the charges of the phosphate moieties of the phosphoinositid e. A cell can be treated with the membrane-permeant phosphoinositide, which is then absorbed into the cell. The neutralizing groups can be removed intracellularly to afford the charged phosphoinositide.