| 摘要 |
<p>A flow directed microcatheter (10) is formed having a gradually changing flexibility and diameter between a proximal end (A) and a distal end (B) of the microcatheter (10). The changing properties of the microcatheter (10) according to the present invention provide the flexibility of the distal tip (44) needed to allow the microcatheter (10) to be directed by the flow of blood within the vasculature, the columnar strength and torquability at the proximal end (A) and along the length of the microcatheter (10) needed to advance, and direct the distal tip to the target site. A proximal segment (A) of the microcatheter (10) includes a plurality of strands which vary in diameter to change the flexibility of the microcatheter (10). A distal segment (B) of the microcatheter (10) includes an inner layer (46) which is compatible with solvents, such as DMSO, and an outer layer (48) which provides strength and flexibility. The proximal segment (A), and the distal segment (B) of the microcatheter (10) are joined by a kink resistant fuse joint (12).</p> |
