| 摘要 |
<p>Disclosed is a process for the manufacture of acetic acid anhydride in the liquid phase which comprises the steps of: (1) continuously feeding to a first reaction zone (i) a reactant compound selected from methyl acetate, dimethyl ether or a mixture thereof, (ii) methyl iodide, (iii) dissolved catalyst components comprising rhodium and one or more promoters, (iv) acetic acid solvent, and (v) carbon monoxide, wherein the carbon monoxide is fed below the surface of the liquid reaction mixture to produce a first liquid reaction comprising components (i), (ii), (iii) and (iv) as well as (v) dissolved carbon monoxide and (vi) acetic anhydride product; (2) feeding the first liquid reaction mixture to a second reaction zone in which is maintained a liquid phase and an overhead vapor space under a total pressure of 40 to 50 bar absolute, no carbon monoxide being fed below the surface of the liquid phase, and the residence time of the liquid phase in said second reaction zone being at least 2 minutes to produce a second liquid reaction mixture comprising components (i), (ii), (iii), (iv), (v) and (vi), and (3) removing the second liquid reaction mixture from the second reaction zone. The second liquid reaction mixture contains less dissolved carbon monoxide than the first liquid reaction mixture.</p> |
