发明名称 1-[(1-SUBSTITUTED-4-PIPERIDINYL)METHYL]-4-PIPERIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THESE COMPOUNDS
摘要 Compounds represented by general formula (I) or physiologically acceptable acid addition salts thereof and medicinal compositions containing these compounds as the active ingredient, wherein Ar represents (Ar-1) or (Ar-2); and A represents -Z-N(Q1)(Q2), -CO-R7 or -(CH2)p-CH(R8)-COR9. Because of exhibiting strong affinity for 5-HT4 receptor, these compounds are useful as drugs for accelerating the peristalsis or drugs for improving digestive tract functions.
申请公布号 CA2330475(A1) 申请公布日期 1999.11.04
申请号 CA19992330475 申请日期 1999.04.19
申请人 DAINIPPON PHARMACEUTICAL CO., LTD. 发明人 TOYOTOMI, YOSHIHITO;TATEISHI, HIROTAKA;MORIKAGE, YUKIKO;MORIKAGE, KAZUO;YOSHIDA, NAOYUKI;KATO, SHIRO;HARADA, HIROSHI
分类号 A61K31/445;A61K31/495;A61K31/535;A61K31/54;A61P1/00;C07D211/58;C07D211/96;C07D405/12;C07D405/14;(IPC1-7):C07D211/58 主分类号 A61K31/445
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