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发明名称 INHIBITORS OF IMPDH ENZYME
摘要 The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
申请公布号 WO9955663(A1) 申请公布日期 1999.11.04
申请号 WO1999US09005 申请日期 1999.04.26
申请人 VERTEX PHARMACEUTICALS INCORPORATED;SAUNDERS, JEFFREY;ELBAUM, DANIEL;NOVAK, PERRY;NAEGELE, DOUGLAS;BETHIEL, SCOTT;RONKIN, STEVEN;BADIA, MICHAEL;FRANK, CATHARINE;STAMOS, DEAN;WALTERS, WILLIAM;PEARLMAN, DAVID 发明人 SAUNDERS, JEFFREY;ELBAUM, DANIEL;NOVAK, PERRY;NAEGELE, DOUGLAS;BETHIEL, SCOTT;RONKIN, STEVEN;BADIA, MICHAEL;FRANK, CATHARINE;STAMOS, DEAN;WALTERS, WILLIAM;PEARLMAN, DAVID
分类号 A61K31/167;A61K31/18;A61K31/235;A61K31/277;A61K31/357;A61K31/36;A61K31/421;A61K31/422;A61P1/18;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P19/02;A61P29/00;A61P31/12;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07C217/84;C07C233/75;C07C235/66;C07C235/88;C07C237/48;C07C255/60;C07C309/75;C07C311/21;C07C311/29;C07C317/40;C07C323/42;C07C333/08;C07D213/75;C07D263/32;C07D271/06;C07D307/91;C07D317/68;C07D413/12 主分类号 A61K31/167
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