发明名称 Vectors carrying coding sequence for the SpsB protein of Staphylococcus aureus
摘要 spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections. Antagonists against such spsB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsB and for detecting the polypeptide in a host.
申请公布号 US5977085(A) 申请公布日期 1999.11.02
申请号 US19970940767 申请日期 1997.09.30
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 BLACK, MICHAEL T.;O'DWYER, KAREN M.
分类号 G01N33/50;A61K31/7088;A61K38/00;A61K38/46;A61K39/00;A61K39/02;A61K39/395;A61K45/00;A61K48/00;A61P31/00;A61P31/04;C07K14/31;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/48;C12N9/52;C12N9/56;C12N15/09;C12N15/31;C12Q1/68;G01N33/15;G01N33/53;(IPC1-7):A61K48/00;C12N15/57;C12N15/63 主分类号 G01N33/50
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