发明名称 |
Retrotransposon and methods |
摘要 |
The present disclosure provides retrotransposons and retrotransposon derivatives and methods for their uses. Specifically, the present invention provides Ty5-6p and derivatives. Ty5-6p and its derivatives integrate preferentially in the genome of eukaryotes in silent chromatin and in regions like silent chromatin. Ty5-6p insertions can be used to regulate the life span of cells, to genetically mark cells, to deliver gene therapy and to identify genes involved in development and in senescence.
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申请公布号 |
US5976795(A) |
申请公布日期 |
1999.11.02 |
申请号 |
US19960771602 |
申请日期 |
1996.12.20 |
申请人 |
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. |
发明人 |
VOYTAS, DANIEL F.;ZOU, SIGE |
分类号 |
A61K48/00;C12N15/81;C12N15/90;(IPC1-7):C12Q1/68;C12N15/87;C12N1/16;C07H21/04 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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