发明名称 |
Antiproliferative protein from Bacillus thuringiensis var. thuringiensis |
摘要 |
The present invention provides an isolated and purified protein derived from Bacillus thuringiensis subspecies thuringiensis, having a molecular weight of approximately 20 kDa of SDS-PAGE, said protein having the partial amino acid sequence shown in SEQ ID No. 1, and wherein said protein displays cytotoxic effects against tumor cells. Also provided is a method of treating a neoplastic cell comprising administering a therapeutically effective dose of the composition of the present invention to said cell, and a method of activating macrophages, comprising administering a therapeutically effective dose of the composition of the present invention to said macrophages.
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申请公布号 |
US5977058(A) |
申请公布日期 |
1999.11.02 |
申请号 |
US19970825896 |
申请日期 |
1997.04.02 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION;UNIVERSIDAD AUTONOMA DE NIEVO LEON |
发明人 |
AGGARWAL, BHARAT B.;RODRIGUEZ-PADILLA, CRISTINA |
分类号 |
C07K14/32;(IPC1-7):C07K14/32 |
主分类号 |
C07K14/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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