发明名称 |
Adjuvant composition containing synthetic hydrophobic lipopolysaccharide |
摘要 |
According to the present invention the adjuvants comprise an emulsion containing at least one synthetic hydrophobic lipopolysaccharide, which can either or not be provided with anionic groups, while maintaining the overall hydrophobicity, an interface-forming constituent (such as an oil) and optionally an aqueous solute. In particular the adjuvant and vaccines prepared with it contain a lipopolysaccharide which had an HLB value of less then 9, more favorably less than 4.
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申请公布号 |
US5976538(A) |
申请公布日期 |
1999.11.02 |
申请号 |
US19960748787 |
申请日期 |
1996.11.15 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
HILGERS, LUCAS A.T.;PLATENBURG, PETER-PAUL L.I. |
分类号 |
A61K47/00;A61K39/39;A61K47/36;A61K47/44;A61P37/00;A61P37/04;(IPC1-7):A61K39/106;A61K9/127;A61K39/335;A61K31/715 |
主分类号 |
A61K47/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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