发明名称 |
Sulfated disaccharide inhibitors of selectins, methods for synthesis and therapeutic use |
摘要 |
Sulfated disaccharides characterized by the ability to inhibit the binding of selectin to its physiologically-relevant ligand are disclosed. Included are efficient and inexpensive methods for producing the sulfated disaccharides, and methods for their therapeutic use and in in vivo and in vitro assays.
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申请公布号 |
US5977080(A) |
申请公布日期 |
1999.11.02 |
申请号 |
US19980004598 |
申请日期 |
1998.01.08 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ROSEN, STEVEN D.;BERTOZZI, CAROLYN |
分类号 |
A61K38/45;C07H3/04;C07H5/10;C07H11/00;C07H15/10;(IPC1-7):A61K31/70;C07H15/00 |
主分类号 |
A61K38/45 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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