| 摘要 |
Disclosed herein are pharmaceutical preparations which are suitable for the treatment of postoperative ileus and contain at least one compound of the formula I in which R1 is Ar, cycloalkyl having 3-7 C atoms or cycloalkylalkyl having 4-8 C atoms, R2 is Ar, or R1 and R2 together are R3 is H, OH, OA or A, R4 is A or phenyl which can optionally be mono- or disubstituted by Hal, OH, OA, CF3, NO2, NH2, NHA, NHCOA, NHSO2A and/or NA2, R5 is OH, CH2OH, R6 and R7 in each case independently of one another are H, Hal, OH, OA, CF3, NH2, NHA, NA2, NHCOA, NHCONH2, NO2 or methylenedioxy, with the oxy groups bonded to adjacent carbons on the ring, A is alkyl having 1-7 C atoms, Ar is a mono- or bicyclic aromatic radical which can optionally contain an N, O or S atom in the ring and can be mono-, di- or trisubstituted by A, Hal, OH, OA, CF3, NH2, NHA, NA2, NHCOA and/or NHCONH2, D is CH2, O, S, NH, NA, -CH2-CH2-, -CH=CH-, -CH2NH-, -CH2-NA- or a bond and Hal is F, Cl, Br or I.
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