发明名称 |
Programmed cell death and caspase-12 |
摘要 |
This invention relates to nucleic acids encoding caspase-12, proteins encoded by casp-12 nucleic acids, vectors, and hosts transformed with vectors. Caspase-12 is a member of the caspase family, which also includes mammalian interleukin-1beta-converting enzyme (ICE). Caspases are thought to carry out the execution phase of apoptosis in a cascade of proteolytic events. The invention also relates to the use of caspase-12 to induce programmed cell death. |
申请公布号 |
AU3492899(A) |
申请公布日期 |
1999.11.01 |
申请号 |
AU19990034928 |
申请日期 |
1999.04.14 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
JUNYING YUAN;NOBUHIRO MORISHIMA |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P35/00;A61P43/00;C07H21/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/50;C12N9/64 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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