| 摘要 |
A method of providing a vascularized, three-dimensional tissue in a living subject is disclosed. The method includes the steps of (a) creating, from a biocompatible material capable of supporting cell adhesion, growth, and migration, a porous construct containing cells to be transplanted, and (b) delivering the construct into an area of interest in the living subject to form a vascularized three-dimensional tissue. The preferred construct has a dimension in which it is about 50 mu m to about 500 mu m from the outermost surface to the center of the construct. The preferred construct also has an interconnected porous structure having a pore size of from about 10 mu m to no greater than 300 mu m. The cells within the preferred construct are no greater than 250 mu m from an outer surface of the construct. |
