| 发明名称 |
Compounds that inhibit the binding of integrins to their receptors |
| 摘要 |
A method for the inhibition of the binding of alpha 4 beta 1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which alpha 4 beta 1 is involved. |
| 申请公布号 |
AU3563799(A) |
申请公布日期 |
1999.11.01 |
| 申请号 |
AU19990035637 |
申请日期 |
1999.04.15 |
| 申请人 |
TEXAS BIOTECHNOLOGY CORPORATION |
发明人 |
IAN L SCOTT;RAJU G. BORE;RONALD J. BIEDIGER;VANESSA O. GRABBE;JAMAL M. KASSIR;KARIN M. KELLER;SHUQUN LIN;ROBERT V. MARKET;TIMOTHY P. DI KOGAN |
| 分类号 |
C07D317/44;A61K31/16;A61K31/357;A61K31/36;A61K31/38;A61K31/381;A61K31/404;A61K31/4184;A61K31/425;A61K31/427;A61K31/443;A61K31/4433;A61K31/4525;A61K31/495;A61K31/496;A61K31/5377;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P17/00;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P37/08;A61P43/00;C07C233/00;C07D233/02;C07D277/30;C07D317/60;C07D333/20;C07D333/24;C07D333/36;C07D405/00;C07D405/12;C07D405/14;C07D409/00;C07D409/12;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D317/44 |
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