发明名称 Lipids
摘要 Bipolar lipids are described which are able to form complexes with polyanions. The lipids comprise a cationic head linked to a hydrophobic backbone and a hydrophilic tail and are capable of self assembly to form stable complexes in aqueous solutions. The lipids are of particular use for the delivery of bioactive substances such as nucleic acids to cells in vitro and especially in vivo.
申请公布号 AU3430899(A) 申请公布日期 1999.11.01
申请号 AU19990034308 申请日期 1999.04.08
申请人 CELLTECH THERAPEUTICS LIMITED 发明人 MICHAEL ANTHONY WILLIAM EATON;TIMOTHY JOHN NORMAN;DAVID PARKER;TERENCE SEWARD BAKER;ANDREW NEIL CHARLES WEIR;CATHERINE FIONA CATTERALL
分类号 A61K47/30;A61K31/16;A61K38/00;A61K45/00;A61K47/48;A61K49/00;A61P43/00;C07C235/10;C07C235/12;C07C237/10;C07C271/20 主分类号 A61K47/30
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