ANTICOAGULANT

摘要

An antithrombotic agent containing effective ingredient dermatan sulfates or pharmacologically acceptable salts thereof (DS) combined with t-PA as effective ingredients. Combined use of DS with tissue plasminogen activator (t-PA) markedly enhances thrombolysis and decreases the dose of t-PA. These agents are useful for the treatment and prevention of various thrombotic diseases such as myocardial infarction, disseminated intravascular coagulation syndrome (DIC), etc. Furthermore, the agents prevent the coagulation of blood during extracorporeal circulation in haemodialysis for patients suffering from renal disease and so forth.