发明名称 |
NOVEL MUTATIONS IN THE FREAC3 GENE FOR DIAGNOSIS AND PROGNOSIS OF GLAUCOMA AND ANTERIOR SEGMENT DYSGENESIS |
摘要 |
The invention features novel mutations in the FREAC3 gene. Our discovery provides methods for early diagnosis of glaucoma, other disorders of the eye, and heart defects. Also provided are cells having at least one deficient FREAC3 gene. Such cells may be used to detect therapeutic compounds that mimic FREAC3, are agonists of FREAC3, or otherwise modulate the level of FREAC3 biological activity.
|
申请公布号 |
CA2325663(A1) |
申请公布日期 |
1999.10.28 |
申请号 |
CA19992325663 |
申请日期 |
1999.04.16 |
申请人 |
UNIVERSITY OF ALBERTA |
发明人 |
JORDAN, TIM;WALTER, MICHAEL A.;RAYMOND, VINCENT |
分类号 |
A01K67/027;A61K48/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;C12Q1/68;G01N33/53;G01N33/566;G01N33/68;(IPC1-7):C12Q1/68;C12N15/12 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|