PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO[3.1.0]HEXAN-2-ONE

摘要

A process for the preparation of cis-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one which comprises either: 1) reacting a sulphonic ester of beta , beta -dimethyl- gamma -(hydroxymethyl)- gamma -butyrolactone with a compound of formula M(C1-6 alkoxide)y, in a suitable solvent; or 2) reacting a C1-4 alkyl ester of 4,5-epoxy-3,3-dimethylpentanoic acid with M(C1-6 alkoxide)y, in a suitable solvent; wherein M is a suitable cation and y fulfills valency requirements.