METHOD FOR PRODUCING SOLID, SPHERICAL FORMS CONTAINING PHARMACEUTICAL ACTIVE AGENTS IN A BINDER MATRIX

摘要

The invention relates to a method for producing solid, spherical forms containing at least one pharmaceutical active agent homogeneously dispersed in an auxiliary matrix. According to this method, the constituents are mixed to form a melt which is then shaped. The invention is characterised in that at least one pharmaceutical active agent is processed with at least one thermoplastically processable matrix auxiliary to form a homogeneous melt with a viscosity of less than 5000 mPas and in that this melt is shaped into drops using a rotating perforated roll. These drops are then cooled so that they solidify.