CRYSTALLOGRAPHICALLY STABLE AMORPHOUS CEPHALOSPORIN COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME

摘要

Yellow and powdery compositions consisting of particles composed of a homogeneous mixture of amorphous cefditoren pivoxil with a water-soluble polymer additive and being orally administrable. These compositions can be obtained by dissolving crystalline cefditoren pivoxil and the water-soluble polymer additive in an aqueous solution of an acid, neutralizing, coprecipitating, and then drying the thus obtained precipitate followed by the recovery of the above-mentioned product in the form of particles.