发明名称 Modulators of molecules with phosphotyrosine recognition units
摘要 The present invention relates to novel organic compounds, to methods for their preparation, to compositions containing them, to their use for treatment of human and animal disorders, to their use for purification of proteins or glycoproteins, and to their use in diagnosis. The invention relates to modulation of the activity of molecules with phospho-tyrosine recognition units, including protein tyrosine phosphatases (PTPases) and proteins with Src-homology-2 domains, in in vitro systems, microorganisms, eukaryotic cells, whole animals and human beings. The novel organic compounds are compounds of formula (I)(L)n-Ar1-R1A(I)wherein (L)n, n, Ar1, R1 and A are as defined in the application.
申请公布号 US5972978(A) 申请公布日期 1999.10.26
申请号 US19990252883 申请日期 1999.02.19
申请人 NOVO NORDISK A/S 发明人 ANDERSEN, HENRIK SUNE;MOLLER, NIELS PETER HUNDAHL;MADSEN, PETER
分类号 C07D231/20;C07D249/14;C07D257/04;C07D271/10;C07D271/113;C07D277/34;C07D285/08;C07D285/12;C07D285/125;C07D285/135;C07D417/06;C07F9/38;(IPC1-7):A61K31/41;C07D285/10 主分类号 C07D231/20
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