发明名称 Synthetic endogenous cannabinoids analogues and uses thereof
摘要 The present invention relates to a compound of the general formula (I) which is a non-hydrolysable analogue of endogenous cannabinoids, which are found to be more potent therapeutic agents as they are more stable, for example, to hydrolytic cleavage in the gastrointestinal tract. The cannabinoid analogues of the invention have a therapeutic value. Therefore, pharmaceutical compositions comprising as active ingredient a therapeutically effective amount of at least one compound of the invention may be prepared. Such compositions may be used as anti-inflammatory, anti-asthmatic, analgetic, hypotensive, antiemetic or anti-spasmodic compositions, and as compositions for treating and/or preventing glaucoma or migraine, or as compositions for relieving symptoms of multiple sclerosis and mood stimulating compositions.
申请公布号 AU3165399(A) 申请公布日期 1999.10.25
申请号 AU19990031653 申请日期 1999.03.30
申请人 YISSUM RESEARCH DEVELOPMENT__COMPANY OF THE HEBREW UNIVERSITY O 发明人 RAPHAEL MECHOULAM;ESTHER FRIDE;SHIMON BEN SHABAT;TZVIEL SHESKIN;AVIVA BREUER
分类号 C07B59/00;C07C43/15;C07C43/178 主分类号 C07B59/00
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