| 摘要 |
Mammalian eyes, corneas, or cornea-containing portions thereof are cultured under defined conditions as an organ culture system. The system of the invention, compared to cell culture, far more closely resembles an in vivo testing system in terms of maintaining the corneal architecture and natural interaction between epithelial cells and other cells residing in the ocular surface. The organ culture system of the invention is sensitive, efficient, economical and reliable for evaluating the potential of a chemical or formulation to cause eye irritation or injury and can be used in the safety tests of consumer products. |
