Device for the transdermal delivery of diclofenac

摘要

The present invention provides a pressure sensitive skin adhesive comprising:(a) a copolymer of one or more alkyl(meth)acrylates containing 4 to 12 carbon atoms in the alkyl group and one or more hydrophilic monomers;(b) a mixture of penetration enhancers comprising:(i) an alkyl ester of an aliphatic monocarboxylic acid containing 1 to 5 carbon atoms in the alkyl group(ii) an alkyl pyrrolidone and(iii) an alkane polyol(c) a therapeutically effective amount of diclofenac or a pharmaceutically acceptable salt thereof.Further provided is a transdermal drug delivery device containing the pressure sensitive skin adhesive.