| 摘要 |
The present invention relates to compounds and pharmaceutical compositions which inhibit proteases, such as cysteine proteases. In particular, the present invention relates to compounds and pharmaceutical compositions which inhibit cysteine proteases of the papain superfamily. The compounds and pharmaceutical compositions of the present invention are useful for treating diseases, particularly parasitic diseases, which are mediated by such proteases. In particular, the present invention relates to a method of treating malaria by inhibiting the cysteine protease falcipain.
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| 申请人 |
SMITHKLINE BEECHAM CORPORATION;THOMPSON, SCOTT, KEVIN;VEBER, DANIEL, FRANK;TOMASZEK, THADDEUS, ANTHONY;TEW, DAVID, GRAHAM |
发明人 |
THOMPSON, SCOTT, KEVIN;VEBER, DANIEL, FRANK;TOMASZEK, THADDEUS, ANTHONY;TEW, DAVID, GRAHAM |
