COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS
摘要
A method for the inhibition of the binding of alpha 4 beta 1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or preventions of diseases states in which alpha 4 beta 1 is involved.
申请公布号
WO9952493(A2)
申请公布日期
1999.10.21
申请号
WO1999US08305
申请日期
1999.04.15
申请人
TEXAS BIOTECHNOLOGY CORPORATION
发明人
SCOTT, IAN, L.;BORE, RAJU, G.;BIEDIGER, RONALD, J.;GRABBE, VANESSA, O.;KASSIR, JAMAL, M.;KELLER, KARIN, M.;LIN, SHUQUN;MARKET, ROBERT, V.;KOGAN, TIMOTHY, P. DI
