| 摘要 |
An apparatus (60) according to the present invention includes a voltage generator (1) for generating brief voltage pulses for the impression of voltage on electrodes (6, 15, 16, 24) included in the apparatus, and a measurement unit (50) which is coupled to the electrodes. These are designed to be secured at or inserted in tissue in a restricted region of a human or an animal in order therebetween to form electric fields in the tissue. The measurement unit (50) is disposed to determine the impedance between the electrodes which is substantially determined by the electric properties of the tissue which is located between the electrodes. A registration and calculator device (10) forms a control unit which, based on the impedance determined by the measurement unit, controls the output voltage of the voltage generator such that the electric field which is formed in the tissue always has a predetermined value. The treatment with the electric field realizes a perforation of cell membranes in the tissue which thereby permits the passage of substances fed to the body (e.g. cytostatic or genetic material).
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