COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS
摘要
A method for the inhibition of the binding of .alpha.4.beta.1 integrin to it s receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or preventions of diseases stat es in which .alpha.4.beta.1 is involved.
申请公布号
CA2328234(A1)
申请公布日期
1999.10.21
申请号
CA19992328234
申请日期
1999.04.15
申请人
TEXAS BIOTECHNOLOGY CORPORATION
发明人
KELLER, KARIN M.;LIN, SHUQUN;KASSIR, JAMAL M.;GRABBE, VANESSA O.;KOGAN, TIMOTHY P.;RAJU, BORE G.;BIEDIGER, RONALD J.;SCOTT, IAN L.;MARKET, ROBERT V.
