| 发明名称 |
MUTANT PROTEINS HAVING LOWER ALLERGENIC RESPONSE IN HUMANS AND METHODS FOR CONSTRUCTING, IDENTIFYING AND PRODUCING SUCH PROTEINS |
| 摘要 |
The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.
|
| 申请公布号 |
CA2327311(A1) |
申请公布日期 |
1999.10.21 |
| 申请号 |
CA19992327311 |
申请日期 |
1999.04.14 |
| 申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
ESTELL, DAVID A.;HARDING, FIONA A. |
| 分类号 |
A23K1/165;A61K38/46;A61P37/08;C11D3/386;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/54;C12N15/09;C12N15/57;C12N15/63;G01N33/50;G01N33/68;(IPC1-7):C12N15/57 |
主分类号 |
A23K1/165 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
