NOVEL NEP II MEMBRANE METALLOPROTEASE AND ITS USE FOR SCREENING INHIBITORS USEFUL IN THERAPY

摘要

The invention concerns an isolated polypeptide comprising an amino acid sequence selected among the sequence SEQ ID n° 2 or n° 4, a sequence derived from or homologous with said sequence SEQ ID n° 2 or n° 4, or a biologically active fragment of said sequence SEQ ID n° 2 or n° 4, said isolated polypeptide being designated as 'NEP II', and the use of said NEP II polypeptide for screening inhibitors useful in therapy.