发明名称 |
PORCINE ADENOVIRUS TYPE 3 GENOME |
摘要 |
The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3) is provided. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals. In addition, PAV3 vectors can be used for gene therapy and expression of heterologous polypeptides. PAV-3 genome sequences can also be used for diagnostic purposes, to detect the presence of PAV-3 DNA in a subject or biological sample.
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申请公布号 |
CA2325574(A1) |
申请公布日期 |
1999.10.21 |
申请号 |
CA19992325574 |
申请日期 |
1999.04.15 |
申请人 |
UNIVERSITY OF SASKATCHEWAN |
发明人 |
BABIUK, LORNE A.;REDDY, POLICE SESHIDHAR;TIKOO, SURESH KUMAR |
分类号 |
G01N33/50;A61K39/235;A61K48/00;A61P31/12;A61P37/04;C07K14/075;C07K16/08;C12N5/10;C12N7/04;C12N15/09;C12N15/861;C12Q1/68;G01N33/53;G01N33/566;(IPC1-7):C12N15/86;A61K38/00;A61K39/00;C07K16/00;C07K14/03 |
主分类号 |
G01N33/50 |
代理机构 |
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主权项 |
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地址 |
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