USE OF MONOCYTES DERIVED CELLS, ANTIGENS AND ANTIBODIES FOR OPTIMAL INDUCTION OF IMMUNOTHERAPEUTIC EFFICIENCY

摘要

The invention relates to monocyte derived cells, in a purified form and substantially free of contaminants, presenting antigenic epitopes on their membranes after interiorization and processing of at least an antigen-antibody complex formed between an antigen and an antibody, under appropriate conditions, said epitopes corresponding to proteolytic degradation products of said antigen, with said antibody being directed against a tumor or against an infectious agent, and with said antigen being fragments of tumor or of infectious agent, including membranes or tumor apoptotic bodies, or purified tumor or infectious antigens or being recombinant tumor or infectious antigens.