| 发明名称 |
USE OF STEROIDAL ALKALOID DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS |
| 摘要 |
The present invention makes available assays and reagents inhibiting paracri ne and/or autocrine signals produced by a hedgehog protein or aberrant activati on of a hedgehog signal transduction pathway, e.g., which involve the use of a steroidal alkaloid or other small molecule.
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| 申请公布号 |
CA2326654(A1) |
申请公布日期 |
1999.10.21 |
| 申请号 |
CA19992326654 |
申请日期 |
1999.04.09 |
| 申请人 |
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
COOPER, MICHAEL K.;BEACHY, PHILIP A.;PORTER, JEFFREY A. |
| 分类号 |
A61K31/56;A61K31/00;A61K31/4355;A61K31/58;A61P17/00;A61P35/00;A61P43/00;C07J69/00;C07J71/00;(IPC1-7):A61K31/585 |
主分类号 |
A61K31/56 |
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