Diagnostic marker

摘要

PCT No. PCT/JP96/00169 Sec. 371 Date Sep. 17, 1997 Sec. 102(e) Date Sep. 17, 1997 PCT Filed Jan. 30, 1996 PCT Pub. No. WO96/23525 PCT Pub. Date Aug. 8, 1996A diagnostic marker containing (a) a detection system such as an antibody and (b) a fluorescent functional group that is bound to the detection system and represented by the following formula: wherein R1 and R2 independently represent hydrogen atom, an alkyl group or the like; R3 represents an alkyl group, a sulfonic acid-alkyl group or the like; X- represents an anion species, if required; Y represents a C1-C10 alkylene group or a C1-C10 alkylene group containing one or more atoms selected from the group consisting of oxygen atom, nitrogen atom and sulfur atom. The diagnostic marker emits fluorescence having a wavelength of 780 nm or more when irradiated with near or far infrared rays, and thus useful for infrared endoscopic diagnosis or identification of a focus in surgical operation.