发明名称 |
Growth factor analogs |
摘要 |
PCT No. PCT/GB96/00052 Sec. 371 Date Dec. 11, 1997 Sec. 102(e) Date Dec. 11, 1997 PCT Filed Jan. 12, 1996 PCT Pub. No. WO96/21676 PCT Pub. Date Jul. 18, 1996A peptide having growth factor type activity (mitogenic and agonist/antagonist for the EGF receptor) which is a TGF- alpha analog but contains a bicyclic Pro analog (for instance D-2-azabicyclo[2,2,1]heptane-3-carboxylic acid), an N-terminal Phe or Trp residue, and a disulfide bridge.
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申请公布号 |
US5969099(A) |
申请公布日期 |
1999.10.19 |
申请号 |
US19970861000 |
申请日期 |
1997.12.11 |
申请人 |
THE SECRETARY OF STATE FOR DEFENCE |
发明人 |
ANDERSON, DEREK W.;MELLOR, JOHN M.;RICHARDS, NIGEL G. J.;SARGOOD, KAREN J.;TURNER, DAVID L.;SHARMA, RAM P.;DAVIES, DONNA E.;CHAMBERLIN, STEPHEN G.;RICHTER, AUDREY |
分类号 |
A61K38/00;C07K14/495;(IPC1-7):C07K7/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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