发明名称 Process for preparing 3-alkoxymethylcephem compounds
摘要 PCT No. PCT/JP97/00708 Sec. 371 Date Nov. 7, 1997 Sec. 102(e) Date Nov. 7, 1997 PCT Filed Mar. 7, 1997 PCT Pub. No. WO97/34027 PCT Pub. Date Sep. 18, 1997A process for preparing a 3-alkoxymethylcephem compound represented by the formula (II) where R1 is a hydrogen atom, amino or protected amino, R3 is a hydrogen atom or carboxylic acid protective group and R4 is lower alkyl, which process is characterized in that a 3-thiomethylcephem compound represented by the formula (I) where R1 and R3 are as defined above and R2 is aryl which may have a substituent, is electrolytically oxidized in an electrooxidation reaction system in the presence of a lower alcohol using as a positive electrode, a material selected from the group consisting of platinum, tin, aluminum, stainless steel, nickel, lead oxide, carbon, iron oxide and titanium, to obtain the 3-alkoxymethylcephem compound.
申请公布号 US5968335(A) 申请公布日期 1999.10.19
申请号 US19970945850 申请日期 1997.11.07
申请人 OTSUKA KAGAKU KABUSHIKI KAISHA 发明人 TORII, SIGERU;TANAKA, HIDEO;SASAOKA, MICHIO;KAMEYAMA, YUTAKA
分类号 C07D501/04;C07D501/60;C25B3/02;(IPC1-7):C25B3/00 主分类号 C07D501/04
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