摘要 |
Novel indole derivatives represented by formula (I) or salts thereof, wherei n R1 is aryl-substituted lower alkyl in which the aryl may be substituted by a t least one member selected among halogen atoms, aryls, heterocyclic groups, aryl-substituted lower alkyls, aryl-substituted lower alkenyls, lower haloalkyls, (lower cycloalkyl)-substituted lower alkyloxys, (lower cycloalkyloxy)-substituted lower alkyls, aryl-substituted lower alkynyls, aryloxy-substituted lower alkyls, aryl-substituted lower alkyloxys, lower alkylthios, lower alkyloxys, and alkenyls; and R2 is a lower alkyl, lower alkenyl, aryl, or heterocyclic group optionally substituted by halogeno, low er alkyl, lower alkenyl, or aryl. These compounds have a hypoglycemic activity and a PDE5 inhibitory activity and are useful as a drug.
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申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
YAMASAKI, NORITSUGU;HIRAMURA, TAKAHIRO;KAYAKIRI, HIROSHI;OKU, TERUO;ONOMURA, OSAMU;IMOTO, TAKAFUMI |