发明名称 INDOLE DERIVATIVES
摘要 Novel indole derivatives represented by formula (I) or salts thereof, wherei n R1 is aryl-substituted lower alkyl in which the aryl may be substituted by a t least one member selected among halogen atoms, aryls, heterocyclic groups, aryl-substituted lower alkyls, aryl-substituted lower alkenyls, lower haloalkyls, (lower cycloalkyl)-substituted lower alkyloxys, (lower cycloalkyloxy)-substituted lower alkyls, aryl-substituted lower alkynyls, aryloxy-substituted lower alkyls, aryl-substituted lower alkyloxys, lower alkylthios, lower alkyloxys, and alkenyls; and R2 is a lower alkyl, lower alkenyl, aryl, or heterocyclic group optionally substituted by halogeno, low er alkyl, lower alkenyl, or aryl. These compounds have a hypoglycemic activity and a PDE5 inhibitory activity and are useful as a drug.
申请公布号 CA2327397(A1) 申请公布日期 1999.10.14
申请号 CA19992327397 申请日期 1999.04.05
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 YAMASAKI, NORITSUGU;HIRAMURA, TAKAHIRO;KAYAKIRI, HIROSHI;OKU, TERUO;ONOMURA, OSAMU;IMOTO, TAKAFUMI
分类号 C07D209/10;C07D209/12;C07D405/10;C07D409/10;C07D409/12;(IPC1-7):C07D209/12;A61K31/40 主分类号 C07D209/10
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