发明名称 |
AZATRICYCLIC COMPOUNDS |
摘要 |
A compound of formula (I), wherein X' is nitrogen or carbon bonded to a substituent species characterized as having a sigma m value greater than 0, less than 0 or 0; X is nitrogen or carbon bonded to a substituent species characterized as having a sigma m value equal to 0; A, A' and A" are individually substituent species characterized as having a sigma m value greater than 0, less than 0 or 0; Z' is a substituent other than hydrogen; j is an integer from 0 to 5; and the wavy line in the structure indicates that the compound can exist in the form of an enantiomer or a diasteromer; Z" is hydrogen or a substituent other than hydrogen; Y is C=O, C(OH)R' or C-A, where R' is hydrogen or lower alkyl is provided. |
申请公布号 |
WO9951601(A1) |
申请公布日期 |
1999.10.14 |
申请号 |
WO1999US04324 |
申请日期 |
1999.02.26 |
申请人 |
R.J. REYNOLDS TOBACCO COMPANY;CROOKS, PETER, ANTHONY;DEO, NIRANJAN, MADHUKAR |
发明人 |
CROOKS, PETER, ANTHONY;DEO, NIRANJAN, MADHUKAR |
分类号 |
A61K31/444;A61P25/00;A61P43/00;C07D471/18;(IPC1-7):C07D471/18 |
主分类号 |
A61K31/444 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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