SMALL BORE BIOLOGIC GRAFT WITH THERAPEUTIC DELIVERY SYSTEM

摘要

A composite graft (10) for a fluid-carrying vessel in a living body, comprising: an inner vessel (12) comprising a biologic collagenic material that has been stabilized, an outer member (14) surrounding at least a segment of the inner vessel (12) and defining an annulus (16) between the inner vessel (12) and the sleeve (14), the outer member (14) comprising a polymeric fabric, and a bioactive compound in said annulus (16), said bioactive compound being carried on a time-release vehicle. The bioactive compound is preferably an occlusion-preventing agent. Alternatively, the sleeve (14) includes the bioactive compound, either on its inner surface or integrally as part of its fibers.