| 摘要 |
<p>The present invention provides a pressure sensitive skin adhesive comprising: (a) a copolymer of one or more alkyl(meth)acrylates containing 4 to 12 carbon atoms in the alkyl group and one or more hydrophilic monomers; (b) a mixture of penetration enhancers comprising: (i) an alkyl ester of an aliphatic monocarboxylic acid containing 1 to 5 carbon atoms in the alkyl group; (ii) an alkyl pyrrolidone and (iii) an alkane polyol; (c) a therapeutically effective amount of diclofenac or a pharmaceutically acceptable salt thereof. Further provided is a transdermal drug delivery device containing the pressure sensitive skin adhesive.</p> |
