发明名称 |
N-TERMINALLY TRUNCATED GLP-1 DERIVATIVES |
摘要 |
The present invention relates to N-terminally truncated derivatives of human glucagon-like peptide-1 (GLP-1) and analogues thereof having a protracted profile of action, as well as the use of such derivatives in pharmaceutical compositions for the treatment of obesity, insulin dependent or non-insulin dependent diabetes mellitus. The GLP-1 derivatives have a lipophilic substituent attached to at least one amino acid residue.
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申请公布号 |
WO9943705(A8) |
申请公布日期 |
1999.10.14 |
申请号 |
WO1999DK00081 |
申请日期 |
1999.02.25 |
申请人 |
NOVO NORDISK A/S |
发明人 |
KNUDSEN, LISELOTTE, BJERRE;HUUSFELDT, PER, OLAF |
分类号 |
C12N15/09;A61K38/00;A61K38/22;A61K38/26;A61K38/28;A61P3/04;A61P3/10;A61P5/50;C07K14/605;(IPC1-7):C07K14/605 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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