MEMBERS OF TNF AND TNFR FAMILIES

摘要

Members of the TNF and the TNFR superfamily of proteins have been identified. These proteins are promising targets for therapeutic intervention and mimesis. TNF-L and TNFR-L proteins can be used to induce cell death and/or profileration of cells. Members of these superfamilies have been implicated in a broad variety of disease processes, making them central biological and physiological regulators.