LIVE ATTENUATED SALMONELLA VACCINE

摘要

The present invention is related to a vaccine for inducing an immune response to a Salmonella strain in an animal, including a human, characterised in that it comprises a pharmaceutically acceptable carrier and a genetically modified Salmonella strain which is in an amount effective to produce an immune response in said animal, including human, and comprises a modification in its wild type DNA sequence SEQ ID NO 09, any of the DNA sequences from the same operon as a wild type DNA sequence selected from the group consisting of SEQ ID NO 01, SEQ ID NO 14, SEQ ID NO 15 and SEQ ID NO 16, and/or any regulatory sequences of any of the said DNA sequences.